So today I found this article published by Neuroscience News June 5, 2017 which only serves to flame my obsession with CBD! Very excited about the possibilities!

Cannabis Compound Could Unlock New Cognitive Treatment for Schizophrenia

Summary: According to researchers, Cannabidiol, an active compound in cannabis plants, could help to alleviate cognitive impairment in people with schizophrenia.

Source: IHMRI.

IHMRI researchers have discovered that an active compound in cannabis plants may alleviate cognitive impairment, providing a vital opportunity in the treatment of schizophrenia.  LET THAT SINK IN!!!

The compound, Cannabidiol (CBD), can influence learning, memory and attention, offering potential solutions to several core symptoms of schizophrenia that can be a challenge to alleviate with existing medicines, such as cognitive impairment.

The researchers hope to use this knowledge to develop new and improved medications for schizophrenia—a debilitating mental illness that ranks among the top 10 causes of disability in developed countries worldwide.

Although current antipsychotic medications are effective against the delusions and hallucinations of schizophrenia, they are less effective in treating the cognitive and negative symptoms, such as social withdrawal and blunted emotional expression. Current medications can also have negative side effects, such as weight gain and movement disorder.

PhD candidate Ashleigh Osborne and her supervisors, Dr Katrina Green and Professor Nadia Solowij from the University of Wollongong (UOW), initially uncovered the fascinating insights about the therapeutic potential of CBD during a detailed review of 27 existing studies.

“From this review, we found that CBD will not improve learning and memory in healthy brains, but may improve aspects of learning and memory in illnesses associated with cognitive impairment, including Alzheimer’s disease, as well as neurological and neuro-inflammatory disorders,” project leader, Dr Katrina Green said. “Evidence suggests that CBD is neuroprotective and can reduce cognitive impairment associated with use of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis.”

This evidence inspired Ms Osborne to investigate whether CBD can improve cognitive impairment in a rodent model of schizophrenia, together with her supervisors and research team members, Senior Professor Xu-Feng Huang and PhD candidate Ilijana Babic.

“We found that CBD was able to restore recognition and working memory, as well as social behaviour to normal levels,” Ms Osborne said.

Image shows a cannabis plant.

The researchers hope to use this knowledge to develop new and improved medications for schizophrenia—a debilitating mental illness that ranks among the top 10 causes of disability in developed countries worldwide. image is for illustrative purposes only.

“These findings are interesting because they suggest that CBD may be able to treat some of the symptoms of schizophrenia that are seemingly resistant to existing medications. In addition, CBD treatment did not alter body weight or food intake, which are common side effects of antipsychotic drug treatment.”

Dr Green said the team was excited about the results but further testing was needed to determine whether CBD has the same beneficial effects in people with schizophrenia. They are now examining changes in neurotransmitter signalling pathways in the brain that result from CBD treatment in order to uncover the underlying therapeutic mechanisms.About this neuroscience research article

Please Note: The researchers do not endorse the use of cannabis products to treat schizophrenia, as some ingredients, such as THC, have the potential to aggravate symptoms. This research examined one isolated compound of the cannabis plant within controlled laboratory settings. People diagnosed with a mental illness should always consult their medical practitioners about any issues with their current medication.

Funding: These studies were supported by the National Health and Medical Research Council (Project Grant 1007593 to Professor Nadia Solowij), the Australian Research Council (Future Fellowship FT110100752 to Professor Nadia Solowij) and a Faculty of Science, Medicine and Health Advancement Grant (2015/SPGA-S/02 to Dr Katrina Green and Senior Professor Xu-Feng Huang). Ashleigh Osborne is supported by an Australian Government Research Training Program Scholarship.

Source: IHMRI
Image Source: image is in the public domain.
Original Research: Abstract for “A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia” by Ashleigh L. Osborne, Nadia Solowij, and Katrina Weston-Green in Neuroscience and Biobehavioral Reviews. Published online January 2017 doi:10.1016/j.neubiorev.2016.11.012A

I would be most interested in hearing from folks who can speak from personal experience about the positive results of using CBD oil and how it is helping you?

This is what triggered my obsession with CBD oil!

When my thirty-four old son’s psychiatric provider recommended CBD oil to help manage his anxiety, I was shocked.  He has a diagnosis of Paranoid Schizophrenia which he received at the age of twenty-four.    As I sat next to him in that tiny office, I couldn’t believe my ears.  My first thought was she must be kidding.  I had heard about CBD oil and had read an article on the so called benefits of CBD, but it was still just a vague notion that I naturally dismissed as ridiculous or better yet “snake oil.” 

So once again, I began my research as I have done diligently for the past ten years every time he was prescribed a new neuroleptic drug. The following is the first thing I learned and what triggered my obsession with CBD oil. 

CBD oil is an oil that includes concentrations of cannabidiol, which is most commonly called CBD. CBD is a cannabinoid. In fact, it is one of many compounds found in the cannabis plant that may hold promise as a medical treatment.  As Medical News Today reports, researchers are interested in exploring the possibility that CBD could help in the treatment of a diverse assortment of conditions, including epilepsy and seizure disorders, addiction, pain, cancer, diabetes, Alzheimer’s disease, and neuropsychiatric and mood disorders.  LET THAT SINK IN!!